Sign Out
Symptoms and signs: Human experience of acute overdose with PREZISTA/rtv is limited. Single doses up to 3200 mg of the oral solution of PREZISTA alone and up to 1600 mg of the tablet formulation of PREZISTA in combination with ritonavir have been administered to healthy volunteers without untoward symptomatic effects.
Treatment: There is no specific antidote for overdose with PREZISTA. Treatment of overdose with PREZISTA consists of general supportive measures including monitoring of vital signs and observation of the clinical status of the patient. Since darunavir is highly protein bound, dialysis is unlikely to be beneficial in significant removal of the active substance.
