Pregnancy: For PICO-SALAX no clinical data on exposed pregnancy are available.
Fertility: Studies in animals have shown no impairment of fertility or embryo-fetal toxicity. In studies with sodium picosulfate alone, embryofetal toxicity has been observed in rats and rabbits at very high doses. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
Breastfeeding: There is no experience with the use of PICO-SALAX in nursing mothers, so the drug should only be used in nursing mothers if clearly needed.