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The usual starting/initial dose of Physiotens is 0.2 mg daily, with a maximum daily dose of 0.6 mg given as two divided doses. The maximum single dose to be administered is 0.4 mg. Adjustments in daily dose should be individualized to the patient's response.
Physiotens can be taken with or without food.
In patients with moderate to severe renal impairment the starting dose is 0.2 mg daily. If necessary and well tolerated the dose can be increased to 0.4 mg daily in patients with moderate renal impairment and to 0.3 mg daily in patients with severe renal impairment (see Precautions).
In patients undergoing hemodialysis the starting dose is 0.2 mg daily. If necessary and well tolerated the dose can be increased to 0.4 mg daily.
Physiotens is not recommended for use in children and adolescents below 18 years due to lack of data on safety and efficacy.
