Pergoveris is contraindicated in patients with: hypersensitivity to the active substances or to any of the excipients; tumours of the hypothalamus and pituitary gland; ovarian enlargement or ovarian cyst unrelated to polycystic ovarian disease and of unknown origin; gynaecological haemorrhages of unknown origin; ovarian, uterine or mammary carcinoma.
Pergoveris must not be used when an effective response cannot be obtained, such as: primary ovarian failure; malformations of sexual organs incompatible with pregnancy; fibroid tumours of the uterus incompatible with pregnancy.