Instruction for Use: The solution must not be sterilised in an autoclave.
Ondansetron Injection should only be admixed with those infusion solutions which are recommended.
Sodium Chloride Intravenous Infusion BP 0.9% w/v, Dextrose Intravenous Infusion BP 5% w/v.
The diluted solution should be used within 24 hours after dilution.
ONDRIN Injection if diluted for administration is recommended to be used immediately and should any storage is warranted must be stored below 30°C and must be used within 24 hrs.
IV doses greater than 8 mg and up to a maximum of 16 mg must be diluted in 50 mL to 100 mL of 0.9% Sodium Chloride Injection or 5% Dextrose Injection before administration and infused over not less than 15 minutes.
ONDRIN doses of 8 mg or less do not need to be diluted and may be administered as a IM or slow IV injection in not less than 30 seconds.
The initial dose of ONDRIN may be followed by 2 additional IV or IM doses of 8 mg 2 to 4 hours apart, or by a constant infusion of 1 mg/h for up to 24 hours.