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Mepolizumab is a humanised monoclonal antibody (IgG1, kappa), directed against human interleukin-5 (IL-5) produced in Chinese hamster ovary cells by recombinant DNA technology.
NUCALA is supplied as a sterile lyophilised powder for subcutaneous injection after reconstitution. Upon reconstitution with 1.2 mL of Sterile Water for Injection, the resulting concentration is 100 mg/mL and delivers 1 mL, with a pH of 7.0.
Excipients/Inactive Ingredients: Sucrose, Sodium phosphate dibasic heptahydrate, Polysorbate 80, Hydrochloric acid.
