Pregnancy. Severe disturbances of liver function. Dubin-Johnson and Rotor syndromes. Previous or existing liver tumours. History during pregnancy of idiopathic jaundice, severe pruritus or herpes gestationis (also known as pemphigoid gestationis). Current thromboembolic processes.
Reasons for immediate discontinuation of the tablets: Occurrence for the first time of migrainous headaches or more frequent occurrence of unusually severe headaches, sudden perceptual disorders (e.g. disturbance of vision or hearing), first signs of thrombophlebitis or thromboembolic symptoms, a feeling of pain and tightness in the chest, pending operations (six weeks beforehand), immobilization (for instance, following accidents), onset of jaundice, hepatitis, general pruritus, significant rise in blood pressure, pregnancy.