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Each pre-filled syringe contains 6 mg of pegfilgrastim* in 0.6 ml solution for injection. The concentration is 10 mg/ml based on protein only**.
*Produced in Escherichia coli cells by recombinant DNA technology followed by conjugation with polyethylene glycol (PEG).
** The concentration is 20 mg/ml if the PEG moiety is included.
The potency of this product should not be compared to the potency of another pegylated or non-pegylated protein of the same therapeutic class. For more information, see Pharmacology: Pharmacodynamics under Actions.
Excipient(s) with known effect: Each pre-filled syringe contains 30 mg sorbitol (E420).
Each pre-filled syringe contains less than 1 mmol (23 mg) sodium (see Precautions).
Excipients/Inactive Ingredients: Sodium acetate*, Sorbitol (E420), Polysorbate 20, Water for injections.
*Sodium acetate is formed by titrating glacial acetic acid with sodium hydroxide.
