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Mupirocin is not suitable for ophthalmic or intranasal use. When used on the face, care should be taken to avoid the eyes. Should a possible sensitisation reaction or severe local irritation occur, treatment should be discontinued, the product should be washed off and appropriate alternative therapy for the infection instituted.
As with other antibacterial products, prolonged use may result in overgrowth of non-susceptible organisms.
Mupirocin has not been studied in infants under 1 year old and therefore it should not be used in these patients until further data become available.
Polyethylene glycol in the ointment can be absorbed from open wounds and damaged skin and is excreted by the kidneys. Should be used with caution if there is evidence of moderate or severe renal impairment.
