Sign Out
A small decrease in the clearance of cetirizine (16%) was observed with theophylline (400 mg once a day); while the disposition of theophylline was not altered by
concomitant cetirizine administration.
The extent of exposure to cetirizine was increased by about 40% while the disposition of ritonavir was slightly altered (-11%) further to concomitant cetirizine administration.
The extent of absorption of levocetirizine is not reduced with food, although the rate of absorption is decreased.
In sensitive patients, the concurrent administration of cetirizine or levocetirizine and alcohol or other CNS depressants may cause additional reductions in alertness and impairment of performance.
