Sign Out
UDP-glucuronyl transferases have been identified as the enzymes responsible for metabolism of Lamotrigine. There is no evidence that Lamotrigine causes clinically significant induction or inhibition of hepatic oxidative drug-metabolizing enzymes, and interactions between Lamotrigine and medicinal products metabolized by cytochrome P450 enzymes are unlikely to occur. Lamotrigine may induce its own metabolism but the effect is modest and unlikely to have significant clinical consequences. (See Table 6.)
Click on icon to see table/diagram/image