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Children: The following amounts, or 175 mg/m2 of body surface, administered 4 times daily; under 1 year, 15 to 60 mg; 1 to 3 years; 60 to 120 mg; 3 to 6 years; 120 mg; 6 to 12 years; 150 to 300 mg. (Do not exceed more than 8 tablets in a day unless directed by the physician.)
Infusion soln: Intravenous route.
Posology: Dosing based on patient weight (see the dosing table as follows): (See Table 2.)
Click on icon to see table/diagram/imageThe minimum interval between each administration must be at least 4 hours.
The minimum interval between each administration in patients with severe renal insufficiency must be at least 6 hours.
No more than 4 doses to be given in 24 hours.
Severe renal insufficiency: It is recommended, when giving paracetamol to patients with severe renal impairment (creatinine clearance ≤30 mL/min), to increase the minimum interval between each administration to 6 hours (see Pharmacology: Pharmacokinetics under Actions).
In adults with hepatocellular insufficiency, chronic alcoholism, chronic malnutrition (low reserves of hepatic glutathione), dehydration: The maximum daily dose must not exceed 3g (see Warnings and Precautions).
Method of administration: Parenteral.
Take care when prescribing and administering IFIMOL IV to avoid dosing errors due to confusion between milligram (mg) and milliliter (mL), which could result in accidental overdose and death. Take care to ensure the proper dose is communicated and dispensed.
When writing prescriptions, include both the total dose in mg and the total dose in volume. Take care to ensure the dose is measured and administered accurately.
Do not remove inner container from overwrap until ready for use.
The overwrap is a moisture barrier. The inner container maintains the sterility of the product.
After removing overwrap, check for minute leaks by squeezing the container. Do not use if leaks are found and return for replacement.
Bring the injection bottle to room temperature or preferably to 37°C just before use.
Clean the spout of injection bottle with surgical spirit.
Keep the bottle on a hard surface and insert the cannula of the sterile infusion set into the spout of injection bottle. (Note that the cannula of the infusion set should be inserted fully and not halfway into the spout of the Ifimol IV bottle to avoid leakage.)
For administration hang the bottle upside down.
Inject Intravenously slowly at a rate of about 5 mL/minute.
To admit air, insert a sterile injection cannula on the top of the inverted bottle anywhere above the level of the liquid.
Caution: Even inviable damage to bottle caused during storage or transit, may result in contamination. Do not use if leak found on squeezing, or contents not clear, and return for replacement.
