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Treatment can be initiated with parenteral administration and continued or initiated orally.
Adults: Intrahepatic Cholestasis: 10-25 mg/kg/day orally. Usual Starting Dose: 800 mg/day. Total Daily Dose: Not to exceed 1600 mg.
Maintenance Therapy: 800-1600 mg/day.
Administration: Ademetionine tablets should be swallowed whole and not chewed.
For better absorption of ademetionine and complete therapeutic effect, ademetionine tablets should not be taken with meals.
