Pregnancy: No clinical data on exposed pregnancies are available for deferasirox. Data in animals have shown some reproductive toxicity at maternally toxic doses. The potential risk for humans is unknown.
As a precaution, it is recommended that FERASIRO is not used during pregnancy unless clearly necessary.
FERASIRO may decrease the efficacy of hormonal contraceptives (see Interactions). Women of childbearing potential are recommended to use additional or alternative non-hormonal methods of contraception when using FERASIRO.
Breast-feeding: In animal data, deferasirox was found to be rapidly and extensively secreted into maternal milk. No effect on the offspring was noted. It is not known if deferasirox is secreted into human milk. Breast-feeding while taking FERASIRO is not recommended.
Fertility: No fertility data is available for humans. In animals, no adverse effects on male or female fertility were found.