Dydrogesterone is used on its own or together with other medicines to treat conditions caused by progesterone deficiency such as menstrual disorders, infertility, threatened or habitual miscarriage, and endometriosis (a problem caused by abnormal growth of tissues outside the womb).
This medicine may also be used to prevent osteoporosis (thinning and weakening of bones) in postmenopausal women and to relieve mild to moderate symptoms associated with menopause.
Dydrogesterone is also used as part of an assisted reproductive technology as an aid during confirmed pregnancy.
This medicine may be used to treat other conditions as decided by your doctor.
Take Dydrogesterone exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
You may take this medicine with or without food. Try to take it at the same time each day.
The dose of Dydrogesterone will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your condition.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.
DO NOT double a dose under any circumstances.
If you often forget to take your medicine, let your doctor and pharmacist know.
Alert your doctor if you have the following conditions:
- sex hormone-dependent cancer e.g. tumour of the tissue layer covering the brain and spinal cord
- vaginal bleeding with an unknown cause
- severe liver disease
as Dydrogesterone may not be suitable for you.
Do not take this medicine if you are breastfeeding.
Inform your doctor if you have the following conditions:
- current or history of depression
- diabetes
- known blood clotting problems
- cancer
- otosclerosis (abnormal hardening or growth of a bone in the ear)
- systemic lupus erythematosus (an inherited disorder that causes skin or nervous system abnormalities)
- herpes gestationis (a rare type of autoimmune disease that usually occurs during the 2nd or 3rd trimester of pregnancy)
- current or history of porphyria (an inherited disorder that causes skin or nervous system abnormalities)
- liver disease
Let your doctor know if you are pregnant.
Why is it important to keep my appointments with the doctor?
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
- Routine tests (e.g. breast or pelvic exam, screening test of the womb) may be done while you are being treated with Dydrogesterone. Your doctor will advise you about how often you need to have these tests.
- Your blood pressure may rise to unsafe levels without you noticing it. Monitor your blood pressure periodically during treatment).
Dydrogesterone may cause drowsiness or dizziness. If affected, do not drive or take part in any activity in which you need to be alert.
Other side effects may include any of the following: headache, nausea, vomiting, abdominal pain, feeling depressed, and weight gain.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- abnormal vaginal bleeding
- pain, swelling and tenderness in your leg accompanied by redness and warmth
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor and pharmacist if you are taking any of these medicines:
- medicines for epilepsy (fits or seizures) e.g. carbamazepine, phenobarbital, phenytoin
- medicines to treat TB (infection known as tuberculosis) e.g. rifampicin, rifabutin
- medicines for HIV infection e.g. nevirapine, efavirenz
- St. John's wort (herbal medicine)
This list does not include all medicines that may interact with Dydrogesterone.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
Avoid alcohol.
Store in a cool, dry place away from the reach of children. Protect from moisture.
The medicine must not be used past the expiry date.
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