Orion Pharma


Full Prescribing Info
Qualitative and Quantitative composition in terms of active ingredients: "Antifoam M" which is equivalent to dimethicone 100 mg/capsule.
Pharmacology: Cuplaton changes the surface tension of the gastric and intestinal contents, destroying gas bubbles and foaming mucus and enabling gases to coalesce in quantities sufficient to be expelled in the natural way. Cuplaton is nontoxic and is not absorbed by the gastro-intestinal tract, but passes through unchanged. It is excreted as such in faeces.
Flatulence owing to inadequate diet or lack of exercise, for instance during bed rest. Aerophagia. Postoperative bloating. Meteorism due to gastritis or diverticulitis. Gastroscopy and X-ray examination of the gastro-intestinal tract.
The presence of gas in the gastro-intestinal tract is mainly due to aerophagia and decomposition of food during the digestive processes, especially vegetables and unboiled fruit. Both normal and increased quantities of gas in the alimentary canal give rise to trouble, such as pain, bloating and colic.
Silicone defoamers have been used successfully to eliminate the mucus-covered bubbles which obstruct a gastroscopist’s view of the stomach. This led to their trial in treating patients who complain of flatulence and distention. Dimethicone, a physiologically inert silicone, has been given for periods of from 4 weeks to 3 ½ years, in doses of 40 mg four times daily, with excellent or good results and no side effects.
Dosage/Direction for Use
Adults: 1 capsule 3 times daily after meals and 1 capsule at bedtime. 1 capsule 4 times daily for a couple of days prior to gastroscopy and X-ray examination of the gastro-intestinal tract.
Children: Dosage must be individualized by physician.
There are no reports on dimethicone overdose.
Hypersensitivity to dimethicone or to any of the ingredients of the preparation.
Special Precautions
Effects on ability to drive and use machines: Dimethicone does not affect the ability to drive or use machines.
Use In Pregnancy & Lactation
Dimethicone is not absorbed from the gastrointestinal tract, does not cross the placenta and is not excreted in breast milk.
Side Effects
Dimethicone has no known adverse pharmacological effects.
Drug Interactions
Antacids containing aluminium hydroxide and magnesium carbonate adsorb silicone and can impair the effect of dimethicone. Dimethicone may increase the absorption of warfarin and digoxin.
Caution For Usage
Incompatibility: None known.
Store below 30°C in a well-closed container.
Shelf-life: 3 years.
MIMS Class
GIT Regulators, Antiflatulents & Anti-Inflammatories
ATC Classification
A03AX13 - silicones ; Belongs to the class of other drugs used for functional bowel disorders.
Cuplaton cap 100 mg
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