Clopistad Adverse Reactions

The incidence of adverse effects, particularly blood dyscrasias, is lower with clopidogrel, although fatalities have been reported.
Common: Haematoma, epistaxis, gastrointestinal haemorrhage, diarrhoea, abdominal pain, dyspepsia, bruising, bleeding at puncture site.
Uncommon: Thrombocytopenia, leucopenia, eosinophilia, intracranial bleeding, headache, paraesthesia, dizziness, eye bleeding, gastric ulcer and duodenal ulcer, gastritis, vomiting, nausea, constipation, flatulence, rash, pruritus, skin bleeding (purpura), haematuria.
Rare: Neutropenia including severe neutropenia, vertigo, retroperitoneal haemorrhage.
Very rare: Thrombotic thrombocytopenic purpura (TTP), aplastic anaemia, pancytopenia, agranulocytosis, severe thrombocytopenia, granulocytopenia, anaemia, serum sickness, anaphylactoid reactions, hallucinations, confusion, taste disturbances, serious haemorrhage, haemorrhage of operative wound, vasculitis, hypotension, respiratory tract bleeding, bronchospasm, interstitial pneumonitis, gastrointestinal and retroperitoneal haemorrhage with fatal outcome, pancreatitis, colitis, stomatitis, acute liver failure, hepatitis, abnormal liver function test, bullous dermatitis, angioedema, rash erythematous, urticaria, eczema, lichen planus, musculo-skeletal bleeding, arthritis, arthralgia, myalgia, glomerulonephritis, blood creatinine increased, fever.