Reactive airway disease including bronchial asthma or a history of bronchial asthma, severe chronic obstructive pulmonary disease.
Sinus bradycardia, sick sinus syndrome, sino-atrial nodal block, second or third degree atrioventricular block, not controlled with a pace-maker, overt cardiac failure, cardiogenic shock.
Use in neonates and infants (less than 2 years of age); see Dosage & Administration.
Patients receiving monoamine oxidase (MAO) inhibitor therapy.
Patients on antidepressants which affect noradrenergic transmission (e.g. tricyclic antidepressants and mianserin).
Hypersensitivity to the active substances or any of the excipients.