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Pregnancy: There are no adequate data from the use of betahistine in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity (see Pharmacology: Toxicology: Preclinical Safety Data under Actions). Betahistine should not be used during pregnancy unless clearly necessary.
Lactation: It is not known whether betahistine is excreted in human milk. Betahistine is excreted in rat milk. Effects seen post-partum in animal studies were limited to very high doses (see Pharmacology: Toxicology: Preclinical Safety Data under Actions). The importance of the drug to the mother should be weighed against the benefit of nursing and the potential risks for the child.
Fertility: Animal studies did not show effects on fertility in rats.
