Patients with bronchial asthma and history of peptic ulcer need to be carefully monitored during the therapy.
Effects on Ability to Drive and Use Machines: Betahistine is indicated for Meniere's syndrome defined by the triad of core symptoms vertigo, hearing loss, tinnitus and for symptomatic treatment of vestibular vertigo. Both diseases can negatively affect the ability to drive and use machines.
In clinical studies specifically designed to investigate the ability to drive and use machines betahistine had no or negligible effects.