Not to be given in latent or manifested heart insufficiency w/o concomitant treatment. Prinzmetal's angina; bronchial asthma or other chronic obstructive lung diseases; phaeochromocytoma; known ischemic heart disease; peripheral arterial circulatory disorders eg, intermittent claudication; serious acute conditions w/ metabolic acidosis. Risk for interfering w/ carbohydrate metabolism or masking hypoglycaemia. Surgery. Avoid abrupt w/drawal. Not to be given w/ IV verapamil. Combination w/ digitalis. Concomitant use w/ β1
-selective receptor blockers. Not to be taken by patients w/ galactose intolerance, total lactase deficiency or glucose-galactose malabsorption. May affect ability to drive & use machines. Hepatic impairment eg, shunt-operated patients. Severe renal impairment. Not to be given during pregnancy. Lactation. Childn.