View Aprovasc overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to irbesartan, amlodipine or dihydropyridines. Cardiogenic shock, clinically significant aortic stenosis, unstable angina (excluding Prinzmetal's angina). Not to be co-administered w/ aliskiren-containing medicines in patients w/ diabetes or moderate to severe renal insufficiency (GFR <60 mL/min/1.73 m2); ACE inhibitors in patients w/ diabetic nephropathy. Pregnancy & lactation.
NYHA III & IV heart failure; hypertensive crisis; hypertensive patients w/ renal artery stenosis in 1 or both kidneys or severe CHF. Correct vol & Na depletion prior to initiation therapy. Not recommended in concomitant use w/ aliskiren-containing medicines in patients w/ diabetes or moderate to severe renal insufficiency (GFR <60 mL/min/1.73 m2); ACE inhibitors in patients w/ diabetic nephropathy. Hepatic impairment. Women of childbearing potential should use effective contraception. Not to be used during pregnancy. Ped patients.
C09DB05 - irbesartan and amlodipine ; Belongs to the class of angiotensin II receptor blockers (ARBs) and calcium channel blockers. Used in the treatment of cardiovascular disease.
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