Amsubac Side Effects

As with other parenteral antibiotics, the principal side effect observed is injection site pain, especially associated with the IM route of administration. A small number of patients may develop phlebitis or an injection site reaction, after IV administration.
Blood and Lymphatic System: Anaemia, hemolytic anaemia, thrombocytopenia, eosinophilia and leukopenia have been reported during therapy with sulbactam sodium/ampicillin sodium. These reactions are reversible on discontinuation of therapy and are believed to be sensitivity reactions.
Gastrointestinal: The most common were nausea, vomiting, diarrhoea, enterocolitis, and pseudomembranous colitis.
Hepatobiliary Disorders: Bilirubinemia, abnormal hepatic function and jaundice.
Immune System: Anaphylactoid reaction and anaphylactic shock.
Nervous System: Rare reports of convulsions.
Renal and Urinary Systems: Rare reports of interstitial nephritis.
Skin and Subcutaneous Tissue: Rash, itching and other skin reactions, rare reports of Stevens-Johnson syndrome, epidermal necrolysis and erythrema multiforme.
Hepatic: Transient elevations of ALT (SGPT) and AST (SGOT) transaminases. Adverse reactions associated with the use of ampicillin alone may be observed with Ampicillin & Sulbactam.