Xalatan Dosage/Direction for Use

Recommended dosage for adults (including the elderly): Recommended therapy is one eye drop in the affected eye(s) once daily. Optimal effect is obtained if Xalatan is administered in the evening. If one dose is missed treatment should continue with the next dose as normal.
Administration: Pivotal studies have demonstrated that Xalatan is effective as a single drug therapy. Although definitive clinical trials of combination use have not been done a three-month study shows that latanoprost is effective in combination with beta-adrenergic antagonists (timolol). Short-term studies suggest that the effect of latanoprost is additive in combination with adrenergic agonists (dipivalyl epinephrine), oral carbonic anhydrase inhibitors (acetazolamide) and at least partly additive with cholinergic agonist (pilocarpine).
Xalatan may be used concomitantly with other topical ophthalmic drug product to lower intraocular pressure. In case of combined therapy the eye drops should be administered with an interval of at least five minutes apart. The dosage of Xalatan should not exceed once daily since it has been shown that more frequent administration decreases the intra ocular pressure lowering effect.
Children: Safety and effectiveness in children has not been established. Therefore Xalatan is not recommended for use in children.