Herpes zoster (shingles) Adult 1,000 mg 3 times daily for 7 days.
CrCl 15-30 mL/min 1,000 mg twice daily,
<15 mL/min 1,000 mg once daily.
Herpes simplex infections Adult 500 mg twice daily. Duration of treatment: Recurrent episode: 5 days. Initial episode: May have to be extended to 10 days in more severe infection.
CrCl 15-30 mL/min No dose modification.
<15 mL/min 500 mg once daily.