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Pharmacology: Erdosteine pharmacologically acts as a bronchial mucus fluidifying agent. Erdosteine is classified under the mucolytic drugs. Erdosteine beside its property of fluidifying bronchial mucus thus facilitating expectorations, shows effects as antagonizing the formation "in loco" of free radicals and as contrasting the action of elastase enzyme. Pharmacological studies show that Erdosteine, as such, does not possess these properties but only after metabolization, transform into active metabolites which have the chemical -SH groups. These metabolites break the -SH groups and bringing about a reduction in the mucus elasticity and viscosity thus facilitating the expectoration.
The chemical -SH groups, distinctive of this activity, are chemically blocked and become free only after metabolization or in alkaline moiety. This property guarantees a good tolerability without bad tastes and without mercaptanic regurgitations and with good gastric tolerability.
