Rituxsanbe Caution For Usage

Instruction For Use, Handling and Disposal: Intravenous Formulation: Withdraw the required amount of Rituximab under aseptic conditions and dilute to a calculated Rituximab concentration of 1 to 4 mg/mL in an infusion bag containing sterile, non-pyrogenic 0.9%, aqueous saline solution or 5% aqueous dextrose solution. To mix the solution, gently invert the bag in order to avoid foaming. Parenteral medications should be inspected visually for particulate matter and discoloration prior to administration.
The prepared infusion solution of Rituximab is physically and chemically stable for 24 hours at 2°C-8°C and subsequently 12 hours at room temperature.
Incompatibilities: No incompatibilities between Rituximab and polyvinyl chloride or polyethylene bags or infusion sets have been observed.
Disposal of unused/expired medicines: The release of pharmaceuticals in the environment should be minimized. Medicines should not be disposed of via waste-water and disposal through household waste should be avoided. Use established "collection systems", if available in your location.
The following points should be strictly adhered to regarding the use and disposal of syringes and other medicinal sharps: Needles and syringes should never be reused. Place all used needles and syringes into a sharps container (puncture-proof disposable container).
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.