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During shipment, to ensure that there is no loss of potency, the vaccine must be maintained at a temperature of 2° to 8°C (36 to 46°F) or colder, but not exceed temperatures lower than -50°C (-58°F). Use of dry ice may subject ProQuad to temperatures colder than -50°C (-58°F).
Before reconstitution, store the lyophilized vaccine in a refrigerator at 2° to 8°C (36° to 46°F) or colder. The vaccine may also be stored in a freezer and subsequently transferred to a refrigerator; however, the lyophilized vaccine should not be refrozen.
Do not store lyophilized vaccine at room temperature.
If lyophilized vaccine is inadvertently stored at room temperature, it should be discarded.
Protect the vaccine from light at all times since such exposure may inactivate the vaccine viruses.
Discard if reconstituted vaccine is not used within 30 minutes.
The diluent should be stored separately at room temperature (20° to 25°C, 68° to 77°F), or in the refrigerator (2° to 8°C, 36° to 46°F).
Shelf life: 18 months.
