Dosage: Individuals 12 - 23 months of age should receive a first dose of ProQuad administered subcutaneously.
If a second dose of measles, mumps, rubella, and varicella vaccine is needed, ProQuad may be used. This dose is usually administered at 4 to 6 years of age.
If the first dose of a measles-containing vaccine is given between 6 months of age and less than 12 months of age (in an at-risk situation such as measles outbreak, or due to official recommendations) the response to the vaccine may be adversely influenced by circulating maternal antibodies. Therefore, another dose of measles-containing vaccine should be given at 12 months of age or later. A subsequent (third) dose can be administered if warranted by official recommendations for measles-containing vaccine.
At least 1 month should elapse between a dose of measles vaccine or M-M-R II and ProQuad. If for any reason a second dose of varicella-containing vaccine is required, at least 1 month should elapse between administration of the 2 doses.
Do not give immune globulin (IG) or Varicella Zoster Immune Globulin (VZIG) concomitantly with ProQuad (see INTERACTIONS).
Method of Administration: For subcutaneous administration. Do not inject intravascularly.
The vaccine is to be injected in the deltoid region of the upper arm or in the higher anterolateral area of the thigh.