Can cause calls in driving or operating machinery, especially when taken with alcohol; Care should be given to patients with organic disorders in psycho-vegetative and psychosomatic; Patients with drug dependents disorder; Cessation of treatment must be done gradually; Benzodiazepines are given only for a short period of time (2-4), long-term use of clobazam is not recommended; The use of elderly or very weak patients, the dose must be limited to the smallest effective amount; Hypotension; Epilepsy; Amnesia; Paradoxical reaction; Thyroid adenoma; Acute intoxication with CNS depressant drugs; Muscle weakness, ataxia; Glaucoma; Nerve / liver failure and blood dyscrasias; Depression, psychosis and schizophrenia; Drug Dependency.