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Each mL of dexmedetomidine contains dexmedetomidine HCl 8 mcg (equivalent to dexmedetomidine base 100 mcg) and sodium chloride in water 9 mg. The solution is preservative-free and contains no additives and chemical stabilizers.
Dexmedetomidine HCl is a sterile, nonpyrogenic solution suitable for IV infusion following dilution. It is chemically described as (+)-4-(S)-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole monohydrochloride, has a molecular weight of 236.7 and an empirical formula of C13H16N2·HCl.
Dexmedetomidine HCl is a white or almost white powder, freely soluble in water and its pKa is 7.1. Dexmedetomidine is supplied as a clear, colorless, isotonic solution with a pH of 4.5-7.
