Treatment of ischemic symptoms including ulceration, pain & coldness of the extremities in chronic arterial occlusion. Prevention of cerebral infarction recurrence (excluding cardiogenic cerebral embolism).
Not to be administered in patients w/ cerebral infarction until condition has stabilized. Reduce dose or discontinue use if excessive increased pulse rate is observed. Patients w/ bleeding tendency or predisposition to bleeding; coronary artery stenosis; DM or abnormal glucose tolerance; HTN w/ consistently high BP; ventricular/atrial transposition, atrial fibrillation & flutter, ventricular tachycardia & fibrillation, multifocal ventricular ectopics, QTc interval prolongation; during menstruation; asymptomatic cerebral infarction. Closely monitor patients for any anginal symptoms eg, chest pain. Concomitant use w/ anticoagulants, antiplatelet drugs, thrombolytic drugs, prostaglandin E1 or its derivatives. High-fat diet. Long-term use. Severe hepatic impairment & renal impairment. Not to be used during pregnancy & lactation. Low birthwt & suckling infants, newborns, infants & childn. Elderly.
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