Sign Out
Recommended Starting Dose: 10 mg once daily. In patients whose blood pressure is not adequately controlled at this dose, the dose of olmesartan medoxomil may be increased to 20 mg once daily as the optimal dose. If additional blood pressure reduction is required, olmesartan medoxomil dose may be increased to a maximum of 40 mg daily or hydrochlorothiazide therapy may be added.
The antihypertensive effect of olmesartan medoxomil is substantially present within 2 weeks of initiating therapy and is maximal by about 8 weeks after initiating therapy. This should be borne in mind when considering changing the dose regimen for any patient.
In order to assist compliance, it is recommended that Olmetec be taken at about the same time each day, with or without food ie, breakfast time.
Elderly: The maximum dose in elderly patients is olmesartan medoxomil 20 mg once daily, owing to limited experience of higher dosages in this patient group.
Children and Adolescents: The safety and efficacy of olmesartan medoxomil have not been established in children and adolescents up to 18 years.
Renal Impairment: The maximum dose in patients with mild to moderate renal impairment (creatinine clearance 20-60 mL/min) is olmesartan medoxomil 20 mg once daily, owing to limited experience of higher dosages in this patient group.
The use of olmesartan medoxomil in patients with severe renal impairment (creatinine clearance <20 mL/min) is not recommended, since there is only limited experience in this patient group.
Hepatic Impairment: The use of olmesartan medoxomil is not recommended in patients with hepatic impairment, since there is only limited experience in this patient group.
