Adult Start w/ 10 mg once daily & may be increased in patients whose BP is not adequately controlled at this dose to 20 mg once daily as the optimal dose. If additional BP reduction is required, dose may be increased up to a max of 40 mg daily or w/ hydrochlorothiazide therapy. Elderly & mild to moderate renal impairment (CrCl 20-60 mL/min) Max: 20 mg once daily.
Aliskiren. Colesevelam HCl. K supplements & K-sparing diuretics, salt substitutes containing K may lead to increase in serum K. NSAIDs & AIIA may decrease glomerular filtration. Al- or Mg hydroxide-containing antacids reduce bioavailability of olmesartan. Increased serum lithium conc & toxicity during concomitant administration.
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