Lincocin Special Precautions

Review of experience to date suggests that a subgroup of older patients with associated severe illness may less tolerate diarrhea less well. When Lincocin is indicated in these patients, they should be carefully monitored for changes in bowel frequency.
Lincocin should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.
Lincocin, like any drug, should be used with caution in patients with a history of asthma or significant allergies.
The use of antibiotics occasionally results in overgrowth of nonsusceptible organisms particularly yeasts. Should superinfections occur, appropriate measures should be taken. When patients with preexisting monilial infections require therapy with Lincocin, concomitant antimonilial treatment should be given.
During prolonged therapy with Lincocin, periodic liver and renal function studies and blood counts should be performed.
Since adequate data are not yet available in patients with preexisting liver disease, its use in such patients is not recommended at this time unless special clinical circumstances indicate.
Lincomycin has been shown to have neuromuscular-blocking properties that may enhance the action of other neuromuscular-blocking agents. Therefore, it should be used with caution in patients receiving such agents.
Indicated surgical procedures should be performed in conjunction with antibiotic therapy.