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KSR is a film-coated preparation of potassium chloride formulated for slow release.
Each sustained-release film-coated tablet contains potassium chloride 600 mg which is equivalent to 8 mEq each of potassium (K-) and chloride (Cl-).
Mode of Action: The slow- and sustained-release over a period of 6 hrs precludes high concentrations of potassium chloride against a localized area of the gut wall which might irritate or damage the mucosa. The sustained release provides conditions of maximum gastric tolerance and effective absorption for the treatment of all types of potassium deficiency, whether hypochloraemic or hypokalaemic alkalosis. KSR does not alter normal kidney function; can be used in all age groups; replaces the essential chloride anion and potassium, and so prevents hypochloraemic alkalosis.
Treatment and specific prevention of hypokalaemia.
1 or 2 tab 2-3 times daily.
Where KSR is administered routinely with an average daily maintenance dose of an oral diuretic agent, 1 or 2 tab daily may be sufficient.
Administration: KSR tablet should be swallowed whole with a little water preferably during meals.
Advanced renal failure, untreated Addison's disease, acute dehydration, hyperkalaemia, in the presence of obstruction in the digestive tract (eg, resulting from compression of the oesophagus due to dilation of the left atrium or from stenosis of the gut). The administration of KSR in such a situation could be conceivably give rise to ulceration or perforation.
If a patient under treatment with KSR develops severe vomiting, severe abdominal pains or flatulence, or gastrointestinal haemorrhage, the preparation should be withdrawn at once.
In patients with impaired renal function, special care should be exercised when prescribing potassium salts because of the risk of hyperkalaemia. The serum electrolytes should be monitored in these patients and also in patients with congestive heart failure, especially if under treatment with digitalis, in whom hypokalaemia should be avoided.
During KSR administration, laboratory monitoring of serum electrolyte levels should be done periodically.
Oral potassium preparations can provoke gastrointestinal disturbances eg, nausea, vomiting, abdominal pain, diarrhoea. In rare cases, KSR may also cause these side-effects. In this event, reduction in dosage or withdrawal of drug may be necessary.
KSR may have increased risk of hyperkalemia if taken concomitantly with ACE inhibitors, cyclosporin, potassium-sparing diuretics eg, spironolactone, triamterene or amiloride.
Store in a dry place, below 25°C.
A12BA01 - potassium chloride ; Belongs to the class of potassium-containing preparations. Used as dietary supplements.
KSR SR-FC tab 600 mg
100's (Rp490,050/pak)
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