InjHemodialysis 7,500-12,500 IU; IV 5,000-10,000 IU 4 hrly by bolus or continuous infusion in NaCl or dextrose. SC Initially 5,000 IU IV bolus inj then 10,000 IU 8 hrly. Low-dose heparin prophylaxis Patient >40 yr undergoing abdominal or thoracic surgery 5,000 IU SC 2 hr pre-op then 5,000 IU SC 8-12 hrly w/o laboratory control. Topical gel Apply thinly in the affected area 2-3 times daily. May be applied in the gauze then cover the affected area.
Hypersensitivity. Inj: Haemorrhagic diatheses, GI tract ulcers, severe HTN (decompensated), CNS surgical procedures, suspected brain haemorrhage, endocarditis lenta, thyroid operation, suspected malignant tumor w/ risk of bleeding. Not to be given IM for possibility of hematoma. Severe liver, kidney & pancreatic disease as well as imminent abortus in anticoagulant therapy.
Inj: Not for IM administration. Patients w/ disruptive ulcerative lesions, menstruation or hemostatic liver disease. Patients who will undergo surgery & post-op. Discontinue if coagulation test is too long or bleeding occurs. Closely monitor for thrombocytopenia. Patients w/ cardiac arrhythmia given high dose of benzyl alcohol. Pregnancy. Elderly. Topical gel: Not to be applied in mucous membranes or open wounds. Not to be rubbed or massaged in areas w/ thrombosis & thrombophlebitis condition.
Inj: Local or generalized allergic reactions. Transient & reversible hair loss, thrombocytopenia, osteoporosis (long-term therapy). Headache, nausea, itching & increased body temp in anticoagulant therapy. Occurrence of hematoma in prophylaxis of thromboembolism.
B01AB01 - heparin ; Belongs to the class of heparin group. Used in the treatment of thrombosis. C05BA03 - heparin ; Belongs to the class of heparins or heparinoids used topically in antivaricose therapy.
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