Folimid Special Precautions

Pregnant women should avoid using FOLIMID in a dose greater than suggested dose.
Vitamin D should not be used in those with hypercalcemia and vitamin D toxicity.
Supplementary copper should not be used in patients with Wilson's disease (hepatolenticular degeneration), a disease of abnormal copper accumulation, in patients with chronic liver and renal failure should exercise extreme caution in the use of copper supplements.
Supplementary calcium should not be used in patients with hypercalcemia (conditions causing hypercalcemia include sarcoidosis, hyperparathyroidism, hypervitaminosis D and cancer).
Supplementary iron should not be used in patients with iron overload, chronic polyarthritis, bronchial asthma, infectious renal complaints in acute phase, uncontrolled hyperparathyroidism, decompensated hepatic cirrhosis, infectious hepatitis, and during the first trimester of pregnancy.
Betacarotene should be used with caution in patients with impaired renal or liver function because safe use of the drug in the presence of these conditions has not been established.
Riboflavin absorption is increased in hypothyroidism and decreased in hyperthyroidism.
Cyanocobalamin should not be used in those with Leber's optic atrophy (a congenital disorder associated with chronic cyanide intoxication e.g. From tobacco smoke). Decreased levels of vitamin B₁₂ have been associated with reduced ability to detoxify the cyanide in exposed individuals and cyanocobalamin may increase the risk of irreversible neurological damage from optic atrophy in those affected with the disorder. Hydroxocobalamin can help detoxification of cyanide. This form of vitamin B₁₂ is an acceptable form for vitamin B₁₂ supplementation in those with this disorder.