Focyn Dosage/Direction for Use

Intravenous Drip Infusion: The usual daily dosage of Focyn for I.V. use is 2 to 4 g (base) for adults and 100 to 200 mg (base)/kg for children; both of these are given by intravenous drip infusion in 2 divided dose. Each dose is dissolved in 100 to 500 mL of intravenous fluid and infused over a period of one to 2 hours.
For acute and elective abdominal surgery: Adults and children over 12 years: 8 g as a single dose infused intravenous 0.5-1 hour preoperative. Depending on the level of contamination and the length of the surgery, this dose can be repeated. Focyn should be given in combination with an aerobic antibiotics.
Renal insufficiency: Repeated doses should not be given at creatinine clearance below 20 mL/minute.
The dose interval should be 16 hours at 20-40 mL/minute. 8 g of Focyn to be mixed with 500 mL isotonic glucose infusion liquid and to be given at an infusion rate 10-15 mL/minute. Heat is generated when Focyn is resolved. Other Antibiotics or medicaments shall not be added.