PREGNANCY: Administration of drugs during pregnancy should only be considered if the expected benefit to the mother is greater than any possible risk to the foetus.
Salbutamol has been in widespread use for many years in human beings without apparent ill consequence; this includes its well established use in the management of premature labour. However, as with the majority of drugs, there is little published evidence of its safety in the early stage of human pregnancy, but in animal studies there was evidence of some harmful effect on the foetus at very high dose levels.
LACTATION: As salbutamol is probably secreted in breast milk its use in nursing mothers is not recommended unless the expected benefits outweigh any potential risk. It is not known whether salbutamol in breast milk has a harmful effect on the neonate.