Nausea, vomiting, indigestion, diarrhea, stomach cramps, constipation, anorexia w/ wt loss & increased appetite accompanied by wt gain; sedation, tremor, ataxia, headache, nystagmus, diplopia, asterixis, dysarthria, dizziness & incoordination; photosensitivity skin rash, generalized pruritus, erythema multiforme & SJS; emotional disorders, depression, psychosis, aggression, hyperactivity, & destructive behavior; weakness; thrombocytopenia, petechiae, bruising, hematoma formation & hemorrhage, lymphocytosis & hypofibrinogemia, leukopenia, eosinophilia, anemia, & bone marrow suppression; slight increases in serum conc of transaminases (eg, SGPT & SGOT) & LDH, increase in serum bilirubin & abnormal changes in other LFTs; irregular menstruation & secondary amenorrhea, abnormal thyroid function tests; acute pancreatitis; hyperammonemia, hyperglycinemia; edema in extremities.
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