Bicorsan Drug Interactions

Procaterol HCl Hemihydrate must be given with caution if given along with the following medicines.
Joint use of Procaterol HCl Hemihydrate with catecholamine class drugs (eg Epinephrine and Isoproterenol) can cause arrhythmias or, in some cases, cardiac arrest. Epinephrine, Isoproterenol, and other catecholamine groups potentiate the action of adrenoreceptor stimulation of this drug, which may trigger arrhythmias.
Joint use of Procaterol HCl Hemihydrate with Xanthine derivatives (eg. Theophylline, Aminophylline hydrate, and Dipropylline) can worsen hypokalemia and undesirable cardiovascular reactions (e.g. tachycardia and arrhythmias) due to β-adrenergic stimulation. Xanthine derivatives potentiate the action of the adrenoreceptor stimulation of Procaterol, which can result in decreased serum potassium levels and exacerbate unwanted cardiovascular reactions. The mechanism of the cause of hypokalemia induction is unknown. If any abnormalities are found, the dose must be reduced or the use of the drug stopped immediately.
Joint use of Procaterol HCl Hemihydrate with corticosteroids (e.g. Betamethasone, Prednisolone, and Hydrocortisone sodium succinate) or diuretics (e.g. Furosemide) can cause a decrease in serum potassium levels which triggers arrhythmias. Corticosteroids and diuretics increase potassium excretion from the kidney tubules, which may cause a decrease in excess serum potassium levels. If any abnormalities are found, the dose must be reduced or the use of the drug stopped immediately.