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Effects of other medicinal products on baloxavir marboxil or its active metabolite baloxavir: Products that contain polyvalent cations may decrease plasma concentrations of baloxavir. Xofluza should not be taken with products that contain polyvalent cations such as laxatives, antacids or oral supplements containing iron, zinc, selenium, calcium or magnesium.
Immune response to influenza virus: Interaction studies with influenza vaccines and baloxavir marboxil have not been conducted. In studies of naturally acquired and experimental influenza, treatment with Xofluza did not impair the humoral antibody response to influenza infection.
Paediatric population: Interaction studies have only been performed in adults.
