No clinical data on exposed pregnancies are available. Animal studies have shown reproductive toxicity. (see Preclinical Safety Data under Toxicology under Actions.)
Rifaximin is not recommended during pregnancy and in women of child-bearing potential not using contraception. (see Preclinical Safety Data under Toxicology under Actions.)
It is not known whether rifaximin is excreted in human milk. A decision should be taken whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.