Rewisca Drug Interactions

Other medicines and Rewisca: Tell the doctor or pharmacist if taking, have recently taken or might take any other medicines.
Rewisca and certain other medicines may influence each other (interaction). When taken with certain other medicines which have sedative effects (including opioids), Rewisca may potentiate these effects, and could lead to respiratory failure, coma and death. The degree of dizziness, sleepiness and decreased concentration may be increased if Rewisca is taken together with medicines containing: Oxycodone (used as a pain-killer); Lorazepam (used for treating anxiety); Alcohol.
Rewisca may be taken with oral contraceptives.
Concomitant use with opioids: Caution is advised when prescribing pregabalin concomitantly with opioids due to risk of central nervous system (CNS) depression. In a case-control study of opioid users, those patients who took pregabalin concomitantly with an opioid had an increased risk for opioid-related death compared to opioid use alone (adjusted odds ratio [aOR] 1.68 [95% CI 1.19 - 2.36]). This increased risk was observed at low doses of pregabalin (≤300 mg, aOR 1.52 [95% CI 1.04 - 2.22] and there was a trend for a greater risk at high doses of pregabalin (>300 mg, aOR 2.51 [95% CI 1.24 - 5.06]).
Rewisca with food, drink and alcohol: Rewisca capsules may be taken with or without food.
It is advised not to drink alcohol while taking Rewisca.