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Lotemax also contains the following inactive ingredients: Edetate disodium, glycerin, povidone, purified water and tyloxapol. Hydrochloric acid and/or sodium hydroxide may be added to adjust the pH to 5.3-5.6. Benzalkonium chloride 0.01% is added as a preservative.
The suspension is essentially isotonic with a tonicity of 250-310 mOsmol/kg.
Loteprednol etabonate is a white to off-white powder.
Loteprednol etabonate is chloromethyl-17α-[(ethoxycarbonyl)oxy]-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylate. Its molecular formula is C24H31ClO7 and has a molecular weight of 466.96.
