Cream: A white cream containing 1% hydrocortisone with chlorocresol 0.1% as preservative.
Ointment: A white ointment containing 1% of hydrocortisone in an ointment base.
Hydrocortisone is a topically active corticosteroid which has anti-inflammatory, antipruritic and vasoconstrictive actions.
Pharmacology: Corticosteroids are extensively bound to plasma protein.
Only unbound corticosteroids has pharmacological effects or is metabolised. They are metabolised mainly in the liver and also in the kidney, and are excreted in the urine.
Suppression of skin diseases in which inflammation is a prominent feature, e.g. eczema, infantile eczema, atopic dermatitis, dermatitis herpetiformis, contact dermatitis, neurodermatitis, psoriasis and intertrigo.
Apply thinly to the affected area one to four times daily, depending on the seriousness of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions.
If hypothalamic-pituitary-adrenal axis suppression is found, then the drug should be withdrawn, frequency of application reduced or weaker steroid used. Supplemental systemic corticosteroids may be required if signs and symptoms of steroid withdrawal occur.
Hypersensitivity to hydrocortisone, other corticosteroids, or any component in the base.
Discontinue use if irritation, sensitivity or other reaction develop and institute appropriate treatment. Corticosteroid applied to the skin can be absorbed in sufficient amount to produce systemic effects such as hypothalamic-pituitary-adrenal axis suppression, manifestation of Cushing's syndrome, hyperglycaemia and glucosuria. Thus suitable precautions should be taken during prolonged treatment, when treating extensive body surface areas, when using the occlusive technique and when treating children (because of a large skin surface area to body weight ratio). Safety of use of topical corticosteroids during pregnancy and lactation has not been established.
Not suitable for ophthalmic use.
Reported local adverse reactions are burning sensation, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, maceration of the skin, secondary infection, skin atrophy, striae and miliria.
Keep containers well closed. Protect from strong light. Store below 30°C. For external use only.
Recommended shelf-life: 3 years.
D07AA02 - hydrocortisone ; Belongs to the class of weak (group I) corticosteroids. Used in the treatment of dermatological diseases.
H-Cort cream 1%
15 g x 1's;450 g x 1's
H-Cort oint 1%
15 g x 1's;450 g x 1's
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