Special precautions for disposal and other handling: Comprehensive instructions for the administration of Dupixent in a pre-filled syringe are given in Patient Counselling Information.
The solution should be clear to slightly opalescent, colourless to pale yellow. If the solution is cloudy, discoloured or contains visible particulate matter, the solution should not be used.
After removing the 200 mg or 300 mg pre-filled syringe from the refrigerator, it should be allowed to reach room temperature up to 25°C by waiting for 30 min or 45 min before injecting Dupixent, respectively.
The pre-filled syringe should not be exposed to heat or direct sunlight and should not be shaken.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements. After use, place the pre-filled syringe into a puncture-resistant container and discard as required by local regulations. Do not recycle the container.
Incompatibilities: In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.