Dudencer Dosage/Direction for Use

Dudencer is orally taken.
Duodenal ulcer: Recommended dosage: 20 mg once daily. Symptom relief is rapid and healing occurs within 2 weeks. Treatment of 2 weeks further may be required for patients who may not have fully healed after the initial course.
Dosage of 40 mg once daily has been given in patients with poorly responsive duodenal ulcer. Healing is usually achieved within 4 weeks.
The recommended dose of 10 mg once daily is given for the prevention of relapse in patients with duodenal ulcer. The dose may be increased if necessary to 20-40 mg once daily.
Gastric ulcer: Recommended dosage: 20 mg once daily. Symptom relief is rapid and healing occurs within 4 weeks. Treatment of 4 weeks further may be required for patients who may not have fully healed after the initial course.
Dosage of 40 mg once daily has been given in patients with poorly responsive gastric ulcer. Healing is usually achieved within 8 weeks.
The recommended dose of 20 mg once daily is given for the prevention of relapse in patients with poorly responsive gastric ulcer. The dose may be increased if necessary to 40 mg once daily.
Reflux esophagitis: Recommended dosage: 20 mg once daily. Symptom relief is rapid and healing occurs within 4 weeks. Treatment of 4 weeks further may be required for patients who may not have fully healed after the initial course.
Dosage of 40 mg once daily has been given in patients with severe reflux esophagitis. Healing is usually achieved within 8 weeks.
The recommended dose of 10 mg once daily is given for the long-term management of patients with healed reflux esophagitis. The dose may be increased if necessary to 20-40 mg once daily.
Symptomatic treatment of Gastroesophageal Reflux Disease: Recommended dosage: 20 mg daily. Symptom relief is rapid. Patients may respond adequately to 10 mg daily, and therefore individual dose adjustment should be considered.
Further investigation is recommended when symptom control has not been achieved after 4-week treatment with the recommended dosage.
Zollinger-Ellison Syndrome: Recommended initial dosage: 60 mg daily. Individual dose adjustment should be considered and treatment must be continued as long as clinically indicated. All patients with severe disease and inadequate response to other therapies have been effectively controlled and > 90% of the patients maintained on doses of 20-120 mg daily. With doses above 80 mg daily, the dose should be divided and given twice daily.
Impaired renal and liver function: Dose adjustment in patients with impaired renal or liver function is not required.
Children: There is no experience in children.
Elderly: No dose adjustment is necessary in the elderly.