Duodenal & gastric ulcer, reflux esophagitis, symptomatic treatment of GERD 20 mg once daily.
Poorly responsive duodenal & gastric ulcer, severe reflux esophagitis 40 mg once daily.
Prevention of duodenal ulcer relapse, long-term management of healed reflux esophagitis 10 mg once daily, increased to 20-40 mg once daily if necessary.
Prevention of gastric ulcer relapse 20 mg once daily, increased to 40 mg once daily if necessary.
Zollinger-Ellison syndrome Initially 60 mg daily. Maintenance 20-120 mg daily. Dose >80 mg daily should be given in divided doses & bd.